Low-dose hydrocortisone may improve memory in women with human immunodeficiency virus infection

1. Low-dose hydrocortisone (LDH) is well tolerated and improves verbal learning and memory, working memory, and attention in adult women with human immunodeficiency virus (HIV) infection. Evidence Rating Level: 1 (Excellent) Study Rundown: Women with HIV demonstrate deficits in verbal learning, memory, cognition, and increased susceptibility to stress-related cognitive impairment. The hypothalamic-pituitary-adrenal (HPA) axis has